Rejuran has been the newest trending topic in aesthetic and regenerative medicine. Unlike traditional hyaluronic acid skin boosters that primarily provide hydration and temporary plumping, Rejuran separates itself by targeting the skin’s repair and regeneration processes at a cellular level. Its unique constitution and function set it apart as an innovative and therapeutic option for a wide range of dermatologic concerns.
What Makes Rejuran Healer Different?
Rejuran Healer is composed of 100% Polynucleotides (PNs), long chains of DNA fragments purified from a unique source-salmon sperm. These PNs are a more refined and concentrated form of Polydeoxyribonucleotides (PDRN)—an active substance already in human tissues. Because salmon DNA is structurally similar to human DNA, there is high biocompatibility which means a lower risk of immune response.
The Science of Polynucleotides
Polynucleotides function to stimulate the skin’s natural process. It changes the skin using several key mechanisms:
- Fibroblast Activation
PNs stimulate fibroblast which produces collagen and elastin, leading to improved skin structure, elasticity, and production of new skin cells. - Angiogenesis & Tissue Oxygenation
Rejuran enhances blood flow, thereby improving nutrient and oxygen delivery to the skin. - Anti-inflammatory Effects
Polynucleotides reduce inflammation which contributes to faster recovery after procedures and helps inflammatory conditions such as acne scarring or photodamage. - DNA Repair & Antioxidant Protection
PNs support DNA repair within skin cells, protecting against sun damage and slowing cellular aging.
Conclusion
Patients have shifted from wanting to simply fill and hydrate the skin to actively healing and regenerating it. By targeting biological changes of the skin, polynucleotides promote long-term skin health and rejuvenation. For patients looking for natural improvements in skin quality, Rejuran is a promising tool in aesthetic and regenerative medicine.


